Volume 38
Number 1 January 2025Antibiotic-resistance of Gram-negative Urinary Pathogens in a Tertiary Care Hospital in Dhaka
DOI: https://doi.org/10.47648/jmsr.2025.v3801.02
Jannatul Ferdous1 , Syeda Sharmin Duza2 , Taslima Begum3 , Sabeena Shahnaz4 , Saleh Ahmad5 , Tahmina Zahan6
Abstract
Urinary tract infection is one of the most common community-acquired and hospital-acquired infections in Bangladesh as well as around the world. Every year many men and women suffer from UTI and day by day treatment becomes difficult due to the development of antibiotic resistance. Our study aimed to investigate the antibiotic resistance of urinary pathogens isolated at Holy Family Red Crescent Medical College (HFRCMC) from January to December 2018. Out of 4258 urine samples,the total urine-positive samples were 1063. The most common pathogens isolated were Escherichia coli (51.4%), Klebsiella species (38.8%), Pseudomonas species (7.7%), and Acinetobacter species (2.2%%). E. coli and Klebsiella were found highly sensitive to Colistin, Imipenem, Meropenem, Nitrofurantoin, and Amikacin, but almost all were resistant to Cephalosporins and variably sensitive to Amoxiclav, Gentamicin, Ciprofloxacin, Cotrimoxazole, andPiperacillintazobactam. Pseudomonas species were found to havelow-level resistance to colistin, variableresistance to Imipenem and Meropenem, Gentamycin and Amikacin, Ciprofloxacin, and high resistance to Ceftazidime and Cefepime. Acinetobacter was found to be highly sensitive to Colistin and thento Co-trimoxazole. Imipenem, Meropenem, Ciprofloxacin, and Gentamycin showed variable resistance, and Cephalosporine, Amoxiclav, and Piperacillin tazobactam showed high resistance.
Keywords: UTI, E.coli, resistance, gram-negative organism.
- Assistant Professor, Department of Microbiology
- Graduate Research Assistant
- Professor, Department of Microbiology
- Professor, Department of Microbiology
- Assistant Professor, Department of Physical Medicine
- Associate Professor, Department of Pharmacology