Volume 37

Number 2 July 2024

Surgical Site Infection Following Gynecological Oncology Surgery: Microbiological Profile, and Antimicrobial Susceptibility Pattern

DOI: https://doi.org/10.47648/jmsr.2024.v3702.04

Noor-E-Ferdous1 , Sayema Tabassum2 , Arunthiya Shoma Saha3 , Farhana Huq4 , Md. Faizul Ahasan5 , Zaheen Naveed Haque6

Abstract

Background: Surgical site infection (SSI) remains one of the most common postoperative complications following gynecological oncology surgery, contributing to increased morbidity, prolonged hospitalization, and healthcare costs. This study aimed to describe the clinical, surgical, and microbiological characteristics of patients who developed SSI following gynecological oncology surgery. Methods: A descriptive observational study was conducted among patients who developed SSI following gynecologic oncology surgery at Bangladesh Medical University in 2024. A total of 29 patients with confirmed SSI were included. Data on socio-demographic characteristics, clinical factors, surgical variables, SSI type, and outcomes were collected. Microbiological culture and antimicrobial susceptibility testing were performed for bacterial isolates. Results: The mean age of patients was 47.0 ± 14.3 years. Most patients had normal BMI (58.6%), while 34.5% were overweight. Anaemia (75.9%), diabetes mellitus (58.6%), and hypertension (58.6%) were common comorbidities. Contaminated wounds accounted for 55.2% of cases, and 72.4% of patients received perioperative blood transfusion. Superficial incisional SSI was more common (75.9%) than deep incisional SSI (24.1%). No statistically significant association was observed between patient or surgical characteristics and SSI depth. Gram-negative organisms predominated, with Escherichia coli/Enterobacteriaceae being the most frequently isolated pathogen, followed by Klebsiella spp., Pseudomonas spp., and Acinetobacter spp., while Gram-positive organisms included Staphylococcus spp., Enterococcus spp., and Corynebacterium spp. High multidrug resistance (MDR) rates were observed among both gram-negative and gram-positive organisms. Conclusion: SSI following gynecological surgery is associated with significant comorbidities, contaminated wounds, and high antimicrobial resistance rates. Strengthening infection prevention practices and antimicrobial stewardship is essential to reduce SSI burden and improve postoperative outcomes.

Keywords: Surgical site infection, gynecological oncology, antimicrobial resistance, postoperative infection


  1. Associate Professor, Department of Gynecological Oncology

    Bangladesh Medical University, Dhaka

  2. MS, phase B resident, Department of Gynecological Oncology

    Bangladesh Medical University, Dhaka

  3. MS, phase B resident, Department of Gynecological Oncology

    Bangladesh Medical University, Dhaka

  4. MS, phase B resident, Department of Gynecological Oncology

    Bangladesh Medical University, Dhaka

  5. Assistant Professor, Department of Pharmacology

    Ibrahim Medical College and BIRDEM General Hospital, Dhaka

  6. MBBS Student

    Holy Family Red Crescent Medical College and Hospital, Dhaka

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Volume 37, Number 2 July 2024
Page: 22-27