Volume 36

Number 1 January 2024

Association of Serum Lipoprotein (a) with BMI and Waist Circumference in Type 2 Diabetic Patients

DOI: https://doi.org/10.47648/jmsr.2024.v3601.03

Karmakar P1 , Farzana T2 , Akhter S3 , Nahid KA4 , Hussain F5 , Hossain Z6

Abstract

Background: Type 2 diabetes is a widespread chronic condition that originates from a complex interactionbetween genetic and environmental factors, along with contributing risks such as obesity and physicalinactivity. Its associated complications present a significant public health concern worldwide. Dyslipidemiais the most common complication of type 2 diabetes mellitus. Elevated serum lipoprotein(a) is now considereda new lipid-related complication of type 2 diabetes mellitus. Obesity is also considered an essential factorof elevated lipoprotein(a) in type 2 diabetes mellitus. The present study aims to find out the association ofserum lipoprotein(a) with BMI and waist circumference in type 2 diabetic patients. Methodology: The studywas conducted by a hospital-based cross-sectional study of hundred (100) diagnosed type 2 diabetic patientsaged between 31 and 60 years. This study was conducted in the Department of Biochemistry, ChittagongMedical College, and the inpatient & outpatient Department of Endocrinology, Chittagong Medical CollegeHospital. Samples were taken by non-probability consecutive sampling. Essential variables in this study wereFPG, serum lipoprotein(a), BMI, and waist circumference. Results: The mean value of serum level of Lp(a)was raised in type 2 diabetic patients (44.32 ± 2.6 mg/dl). Serum Lp(a) levels were positively and significantlycorrelated with BMI and waist circumference and not associated with fasting plasma glucose. There were alsosignificant differences in BMI and waist circumference in Lp(a) ≤30 mg/dl group and Lp(a) >30 mg/dl group.Conclusions: The results of the present study pointed to the significance of diabetic management in the controlof lipid abnormalities, where the control of obesity is of importance.

Keywords: Serum Lp(a), Type 2 DM, BMI, Waist Circumference.


  1. Assistant Professor, Department of Biochemistry

    Eastern Medical College, Cumilla

  2. Assistant Professor, Department of Biochemistry

    Central Medical College,

  3. Assistant Professor, Department of Biochemistry

    Central Medical College, Cumilla

  4. Associate Professor, Department of Biochemistry

    Eastern Medical College, Cumilla

  5. Assistant Professor, Department of Biochemistry

    Marine City Medical College, Chittagong

  6. Senior Lecturer, Department of Forensic Medicine

    Holy Family Red Crescent Medical College, Dhaka

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Volume 36, Number 1 January 2024
Page: 17-23